Image Gallery: Flush in carcinoid syndrome

What is the cause of the carcinoid flush?

Bradykinin in carcinoid syndrome.

Bradykinin concentrations in peripheral venous blood were measured in seven patients with carcinoid syndrome. The diagnosis was based on typical symptoms and raised urinary excretion of 5-hydroxy-3-indole acetic acid; the carcinoid tumour was verified histologically. Two patients were flushing constantly and the other patients had flushing attacks two to 10 times daily. Several blood samples we...

[Leonine facies in carcinoid syndrome].

Carcinoid syndrome is a rare disorder caused when elevated levels of vasoactive substances secreted by a carcinoid tumor fail to be metabolized by the liver. This can occur for a variety of reasons including metastatic invasion of the organ. Carcinoid syndrome results in elevated levels of 5-hydroxyindoleacetic acid in the urine. Clinical manifestations include: flushing, diarrhea, bronchospasm...

Endobronchial Carcinoid and Concurrent Carcinoid Syndrome in an Adolescent Female

Endobronchial carcinoid tumors are the most common intrabronchial tumors in children and adolescents. Common signs and symptoms include persistent cough and wheezing not responsive to bronchodilators, hemoptysis, and recurrent fever. Diagnosis is frequently made by imaging and direct visualization with flexible bronchoscopy; surgery remains the gold standard treatment, and lung-sparing resectio...

The Carcinoid Syndrome

THE first description of a carcinoid tumour was as early as 1888 (Lubarsch). Later attention was drawn to the possibility that the cells of these tumours (known as argentaffinomas) act as secretors of some "endocrine" substance. "Enteramine" or "serotonin" (5 hydroxytryptamine or 5 H.T.) was later isolated from carcinoid tumours and recently its degradation product-5 hydroxy-indoleacetic acid o...